Nixodine Virginia Tobacco Freebase (0mg Nicotine)
RxVape Virginia Tobacco freebase with Nixodine-S is a bottled alternative for adult vapers who want the flagship Virginia Tobacco profile in a higher-airflow freebase format without nicotine. The active ingredient listed on this product is (S)-6-methylnicotine (6MN), sold here as Nixodine-S. Nicotine content is 0mg.
Quick facts: 120mL bottle · freebase / sub-ohm style · 0mg nicotine · Virginia Tobacco flavor · made in USA · adult recreational use only (21+).
What is Nixodine-S on this product?
On RxVape labels, Nixodine-S refers to a non-nicotine formula based on (S)-6-methylnicotine, a synthetic nicotine analog. It is not the same as standard 0mg juice (flavored VG/PG only), and it is also not the older nicotinamide-only “Nixamide” style formulas some shoppers tried in 2023.
This page is a product listing, not a safety, medical, legal, or drug-testing opinion. Regulatory treatment of nicotine analogs can change. Read labels, check your local laws, and do not treat any analog product as FDA-authorized, FDA-approved, or as a quit-smoking product.
Want a deeper buyer comparison? See What Is Nixodine? Complete Guide and Nixodine vs Nicotine compared.
Flavor and format
This uses RxVape’s Virginia Tobacco direction in a freebase-style bottle intended for sub-ohm tanks, box mods, RDAs, and other higher-airflow setups. If you use a low-wattage refillable pod, the companion Nixodine Virginia Tobacco Nic Salt is the better format match.
Prefer traditional nicotine instead? Choose the live nicotine freebase: Virginia Tobacco Freebase E-Liquid, or the pod-focused Virginia Tobacco Nic Salt (20mg & 50mg).
Ingredients listed on this product
- USDA Certified Organic vegetable glycerin (coconut-derived, USP kosher)
- USP propylene glycol
- Natural and/or artificial flavoring
- Nixodine-S / (S)-6-methylnicotine freebase formula
Label claims on this listing: no nicotine from any source; no diacetyl; no acetyl propionyl. Batch documentation / COA requests can be handled through normal customer support channels when available.
Specifications
- Product type: Nixodine-S freebase e-liquid (non-nicotine)
- Listed active: (S)-6-methylnicotine
- Nicotine content: 0mg
- Format note: freebase-style bottle oriented to sub-ohm / higher-airflow hardware (not a nicotine mg strength chart)
- VG/PG: 60/40
- Flavor: Virginia Tobacco
- Bottle size: 120mL
- Made in: USA
- SKU: RXNIX-FB-120-6
Who this is for
- Adults 21+ who already use nicotine or nicotine-analog vape products
- Sub-ohm / DTL users who want Virginia Tobacco in a freebase bottle
- Shoppers comparing nicotine freebase vs a 0mg-nicotine Nixodine freebase option
Not for: minors, non-users, pregnant people, or anyone seeking a medical, cessation, or “safe vape” product. Analog products can still be habit-forming.
Pod system? Use Nixodine Virginia Tobacco Nic Salt.
Want nicotine freebase? Virginia Tobacco Freebase E-Liquid.
Related reading
Frequently Asked Questions
Does this bottle contain nicotine?
No. This listing is 0mg nicotine. The labeled active is Nixodine-S / (S)-6-methylnicotine, which is chemically distinct from nicotine.
Is Nixodine the same as ordinary 0mg juice?
No. Ordinary 0mg juice is usually only base and flavor. This product includes a listed nicotine-analog ingredient. That does not make it a medical product, a safer product, or a guaranteed match for every nicotine user’s experience.
Is this FDA approved or FDA authorized?
No. Do not read this page as FDA approval, FDA marketing authorization, dietary-supplement authorization, or any government endorsement. RxVape does not market this product as a cessation aid.
Can I use it in my current device?
This freebase bottle is aimed at sub-ohm tanks and higher-airflow devices. For low-wattage pods, choose the Nixodine nic salt version instead. Always follow your device maker’s fill and coil guidance.
Will it pass a drug test?
RxVape does not promise drug-test outcomes. Testing panels, cutoffs, and employer/clinical policies differ, and rules around nicotine analogs can change. If a test result matters for work, sports, court, or medical care, assume risk and get advice from the testing provider—not from a product page.
Is it legal where nicotine/vape products are restricted?
Maybe not. Some places regulate nicotine analogs or inhalation products beyond classic nicotine definitions. Check current local law before buying or shipping. We do not guarantee legality in every jurisdiction.
Adults 21+ only. For adult recreational vapor use. Not for non-users, minors, or pregnant people. May be habit-forming. Not a smoking-cessation product. Not evaluated by the FDA as safe or effective for any therapeutic use.




Jim P. (verified owner) –
Great product and no nicotine still give a kick. Priced right